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Stress, Distress Intolerance, and Drug Dependence

NCT00430482 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 133

Last updated 2019-07-10

Study results available
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Summary

This study is designed to evaluate the relative efficacy of a novel treatment (CBT-IC) versus a standard individual drug-counseling treatment. The novel treatment emphasizes exposure to emotional cues for drug use as part of a comprehensive, yet brief, treatment strategy. These treatments are delivered to opiate-dependent, often poly-substance dependent, individuals in a comprehensive methadone maintenance program who have failed to respond adequately to current treatments.

Conditions

  • Substance Dependence

Interventions

BEHAVIORAL

Cognitive Behavioral Therapy

12 weekly sessions and 3 booster sessions of cognitive behavioral therapy

BEHAVIORAL

Individual Counseling

12 weekly sessions and 3 booster sessions of individual counseling

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Massachusetts General Hospital

    collaborator OTHER

  • Boston University Charles River Campus

    lead OTHER

Principal Investigators

  • Michael W. Otto, Ph.D. · Boston University

  • Mark H. Pollack, M.D. · Rush University

  • Steven A. Safren, Ph.D. · Massachusetts General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-06-30
Primary Completion
2011-07-31
Completion
2011-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00430482 on ClinicalTrials.gov