The Acute Effect of Atorvastain on Renal Function in Patients With Type II Diabetes
NCT00678522 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2008-05-15
Summary
We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium excretion, glomerular filtration rate, tubular function and vasoactive hormones in patients with type II diabetes, not in treatment with insulin.
Conditions
- Healthy Subjects
Interventions
- DRUG
-
80 mg atorvastatin daily on two following days
Sponsors & Collaborators
-
Medical Research
collaborator AMBIG -
Regional Hospital Holstebro
lead OTHER
Principal Investigators
-
Erling B. Pedersen, Professor · Dept. of medical reaserch, Holstebro Hospital, Denmark
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 40 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-09-30
- Primary Completion
- 2008-05-31
- Completion
- 2008-05-31
Countries
- Denmark
Study Locations
More Related Trials
-
Association Between Systemic Exposure of Atorvastatin and Metabolites and Atorvastatin-induced Myotoxicity
NCT00120055 ·Status: COMPLETED ·Phase: PHASE4
-
Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients
NCT03611010 ·Status: COMPLETED ·Phase: PHASE2
-
Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin
NCT00722956 ·Status: COMPLETED ·Phase: PHASE1
-
Improving Diabetic Foot Ulcers With Atorvastatin
NCT00134550 ·Status: COMPLETED ·Phase: PHASE2
-
Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)
NCT00529191 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension
NCT02842359 ·Status: COMPLETED ·Phase: PHASE4
-
Atorvastatin and LDL Profile in Non-Insulin Dependent Diabetes Mellitus
NCT00640549 ·Status: TERMINATED ·Phase: PHASE4
-
Study Comparing Pitavastatin and Atorvastatin in Patients With Type II Diabetes Mellitus and Combined Dyslipidemia
NCT00309751 ·Status: COMPLETED ·Phase: PHASE3
-
Differences in Atorvastatin Metabolite Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity
NCT00199745 ·Status: COMPLETED ·Phase: PHASE4
-
Investigations on Differences in Atorvastatin Metabolites Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity
NCT00414531 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Of Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary Heart Disease (CHD)
NCT00644709 ·Status: COMPLETED ·Phase: PHASE4
-
Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody Titers
NCT00143741 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Of The Efficacy Of Atorvastatin For Lowering Cholesterol In High-Risk Patients With High Cholesterol
NCT00644670 ·Status: COMPLETED ·Phase: PHASE4
-
Cardiopulmonary-bypass and Reno-protective Effect of Atorvastatin Trial
NCT00910221 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
DIATOR-Diabetes Intervention With Atorvastatin
NCT00974740 ·Status: TERMINATED ·Phase: PHASE1
-
Multiple Ascending Dose and DDI Study
NCT03031119 ·Status: COMPLETED ·Phase: PHASE1
-
Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST)
NCT00442845 ·Status: COMPLETED ·Phase: PHASE4
-
Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets
NCT00442325 ·Status: COMPLETED ·Phase: PHASE4
-
CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers
NCT02288338 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Evaluate The Safety And Efficacy Of Atorvastatin In Patients With Diabetes And High Cholesterol
NCT00645424 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Determine the Degree of Additional Reduction in CV Risk in Lowering LDL Below Minimum Target Levels
NCT00327691 ·Status: COMPLETED ·Phase: PHASE4
-
Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.
NCT00404599 ·Status: UNKNOWN ·Phase: PHASE4
-
The HDL Particle Protection Study
NCT02125682 ·Status: COMPLETED ·Phase: PHASE4
-
The Pleiotropic Effects of Atorvastatin When Combined With Common Antihypertenisve Medications.
NCT00656331 ·Status: WITHDRAWN ·Phase: NA
-
The Efficacy and Tolerability of Two Formulations of Atorvastatin In Korean Adult With Hypercholesterolemia
NCT01285544 ·Status: COMPLETED ·Phase: PHASE4