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Veteran Stress and Learning Study

NCT00674570 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 111

Last updated 2019-05-30

Study results available
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Summary

This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms of Posttraumatic Stress Disorder (PTSD). These responses will be tested using a fear learning and memory task administered by computer.

Conditions

  • Stress Disorders, Posttraumatic

Interventions

DRUG

Hydrocortisone

25 mg/oral one hour prior to extinction task

DRUG

D-Cycloserine

50 mg/oral one hour prior to extinction task

DRUG

Placebo

One hour prior to extinction task

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Sabra S Inslicht, PhD · San Francisco VA Medical Center, San Francisco, CA

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-01-13
Primary Completion
2015-06-22
Completion
2015-06-22
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00674570 on ClinicalTrials.gov