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Long Term Minor Sibling Donor Well-Being

NCT00667784 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 2

Last updated 2012-04-02

No results posted yet for this study

Summary

The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member.

Primary Aims:

1. Compare minor donor adjustment to minor non-donor adjustment, including anxiety, self-esteem, traumatic stress, achievement, and behavior.
2. Evaluate minor donor adjustment across time, including self -esteem, traumatic stress, anxiety, achievement, and behavior.
3. Investigate the effect of the following on donor well-being:

* Donor variables: 1) the impact of the harvest, including type of harvest (needle aspiration of bone marrow or peripheral blood stem cell collection by apheresis after injection of G-CSF), pre-procedural anxiety and perceived pain; 2) age of donor at time of transplant, 3) gender, 4) preparedness for transplant, 5) sibling order (for sibling participants), and 6) donor's decision-making and ambivalence regarding donation.
* Recipient variables: 1) the recipient's level of well-being or death, 2) genetic versus acquired disease types, and 3) familial relationship of donor to recipient.
* Family support variables: 1) the distress of the family, 2) the quality of the relationship between the potential donor and the recipient, and 3) parent's well-being (post-traumatic stress disorder or PTSD, depression).

Secondary Aim:

Evaluate satisfaction with the donor program.

Conditions

  • Disorder Related to Bone Marrow Transplantation
  • Blood Stem Cell Transplant Failure
  • Disturbance of Emotions Specific to Childhood and Adolescence
  • Transmission, Blood, Recipient/Donor
  • Sibling

Interventions

BEHAVIORAL

Questionnaire

Questionnaires completed before the bone marrow or stem cells are collected, after the transplant, and 6 months after the transplant.

Sponsors & Collaborators

  • M.D. Anderson Cancer Center

    lead OTHER

Principal Investigators

  • Rhonda Robert, PhD · M.D. Anderson Cancer Center

Eligibility

Min Age
5 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-04-30
Primary Completion
2011-04-30
Completion
2011-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00667784 on ClinicalTrials.gov