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Effects of Remifentanil on Respiratory Function in Mechanically Ventilated Patients

NCT00665119 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2008-12-18

No results posted yet for this study

Summary

Sedation is widely used in mechanically ventilated patients. Propofol, benzodiazepines and opioids are the most used drugs. The study hypothesis is that sedation with remifentanil (an opioid drug) could improved respiratory pattern and effort in mechanically ventilated patients with rapid shallow breathing or high respiratory rate.

Conditions

  • Respiratory Insufficiency
  • Respiration, Artificial
  • Conscious Sedation

Interventions

DRUG

remifentanil

0.05 mcg.kg-1.min-1 for 30 minutes by continuous endovenous infusion

DRUG

placebo

NaCl 0.9 %

Sponsors & Collaborators

  • Fondazione Poliambulanza Istituto Ospedaliero

    lead OTHER

Principal Investigators

  • Giuseppe Natalini, MD · Fondazione Poliambulanza Istituto Ospedaliero

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-04-30
Primary Completion
2008-10-31
Completion
2008-10-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00665119 on ClinicalTrials.gov