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Factorial Study of Metoprolol Succinate TOPROL-XL (324A)

NCT00642096 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1900

Last updated 2009-03-25

No results posted yet for this study

Summary

The purpose of this research study is to determine if treatment with the combination of metoprolol succinate and hydrochlorothiazide is more effective at lowering blood pressure than treatment with either of the two drugs alone. The study will also determine which combined doses of metoprolol succinate and hydrochlorothiazide are most effective at lowering blood pressure (without unacceptable side effects), and whether it is possible to combine both drugs in a single tablet to simplify blood pressure treatment.

Conditions

  • High Blood Pressure (Hypertension).

Interventions

DRUG

Metoprolol Succinate

DRUG

Hydrochlorothiazide

Sponsors & Collaborators

Principal Investigators

  • Vasilios Papademetriou · Georgetown University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-06-30
Primary Completion
2004-07-31
Completion
2004-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00642096 on ClinicalTrials.gov