DZX Mediated Insulin Suppression in Obese Men
NCT00631033 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 51
Last updated 2014-11-06
Summary
The purpose of this study is to determine whether there is an additive effect of metformine on the weight reduction of obese hyperinsulinemic men who are treated with diazoxide.
Conditions
Interventions
- DRUG
- DRUG
-
Diazoxide
- DRUG
-
Metformin + Diazoxide
Sponsors & Collaborators
-
Rijnstate Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-07-31
- Primary Completion
- 2011-12-31
- Completion
- 2011-12-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 Diabetes
NCT05591235 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions
NCT05721729 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Effect of add-on Pioglitazone or Dapagliflozin in Participants With Type 2 Diabetes Mellitus Inadequately Controlled by DPP-4 Inhibitor and Metformin Therapy
NCT03499704 ·Status: COMPLETED ·Phase: PHASE4
-
The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients
NCT03419624 ·Status: TERMINATED ·Phase: PHASE3
-
Effect of Dapagliflozin on 24-hour Blood Glucose in T2DM Patients Inadequately Controlled With Either Metformin Or Insulin
NCT02429258 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of Bexagliflozin Compared to Placebo as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
NCT03259789 ·Status: COMPLETED ·Phase: PHASE3
-
A Placebo Controlled Safety and Efficacy Study of INT131 Besylate in Type 2 Diabetes, With an Active Comparator
NCT00631007 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Bexagliflozin as Monotherapy in Patients With Type 2 Diabetes
NCT02715258 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Tolerability Study of MEDI0382 in Japanese Preobese or Obese Subjects With Type 2 Diabetes
NCT03645421 ·Status: COMPLETED ·Phase: PHASE2
-
Dose-finding of PB-119 Administered Subcutaneously Once-weekly Versus Placebo in Drug-naïve T2DM Subjects
NCT03520972 ·Status: COMPLETED ·Phase: PHASE2
-
A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.
NCT05363774 ·Status: COMPLETED ·Phase: PHASE1
-
Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes
NCT03444584 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus
NCT00308373 ·Status: COMPLETED ·Phase: NA
-
Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy
NCT01514149 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Effect of MEDI0382 on Energy Balance in Overweight and Obese Participants With Type 2 Diabetes Mellitus
NCT03596177 ·Status: COMPLETED ·Phase: PHASE2
-
Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
NCT04195243 ·Status: UNKNOWN ·Phase: PHASE3
-
A Randomized, Double-Blind, Comparator- and Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 Diabetic Patients
NCT01280695 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of TG103 Injection in Overweight/Obese Subjects With Type 2 Diabetes
NCT05063253 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of Pioglitazone and Insulin in Treating Subjects With Type 2 Diabetes Mellitus and Renal Failure.
NCT00770640 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Multiple Oral Doses of JNJ-41443532 in Patients With Type 2 Diabetes Mellitus
NCT01230749 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)
NCT02367066 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Dapagliflozin on Insulin Resistance and Insulin Secretion in Subjects With Type 2 Diabetes
NCT00831779 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Dapagliflozin in Triple Therapy to Treat Subjects With Type 2 Diabetes
NCT01646320 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Pioglitazone
NCT00970424 ·Status: TERMINATED ·Phase: PHASE3
-
Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2)
NCT03074630 ·Status: COMPLETED ·Phase: PHASE4