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Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

NCT00610402 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 57

Last updated 2022-10-20

No results posted yet for this study

Summary

Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face. SWS is also accompanied by an increased pressure within the eye (glaucoma) which can develop very early in life.

Glaucoma represents a group of ocular disorders that are characterized by the loss of retinal ganglion cells and their axons, damage to the optic nerve, and gradual loss of visual field. Recently, several studies provided evidence that there is a potential role of the immune system in the pathogenesis of glaucoma.

These findings suggest that there might be changes in systemic humoral immunity possibly underlying the optic neuropathy in at least some glaucoma patients.

Conditions

  • Sturge - Weber Syndrome (SWS)

Interventions

OTHER

blood sample tear drop sample

blood sample tear drop sample

Sponsors & Collaborators

  • Mainz University

    collaborator OTHER

  • University of California, Irvine

    lead OTHER

Principal Investigators

  • John S Nelson, M.D,PhD · Beckman Laser Institute University of California Irvine

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2007-07-31
Completion
2008-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00610402 on ClinicalTrials.gov