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Effects of Exercise on Endothelial Function in Stroke Patients

NCT00604877 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2008-01-30

No results posted yet for this study

Summary

This study examines the hypothesis that 6 months of treadmill aerobic exercise training improves fibrinolysis (clot defense mechanism) and vasomotor function in chronic hemiparetic (muscular weakness or partial paralysis restricted to one side of the body) stroke patients compared to a control intervention, and that these changes are associated with reduced plasma insulin levels and improved insulin sensitivity / glucose metabolism in this population.

Conditions

  • Stroke
  • Cerebrovascular Disorders

Interventions

BEHAVIORAL

Treadmill Exercise

3 times per week for 6 months, with target of 45 minutes at 60-70% heart rate range

BEHAVIORAL

Stretching/ROM

3 times per week for 6 months, passive and active stretching and range of motion (ROM) exercises for the upper and lower extremities

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    lead NIH

Principal Investigators

  • Frederick M. Ivey, PhD · University of Maryland, Baltimore

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-08-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00604877 on ClinicalTrials.gov