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Bone Disease in Severely Burned Children

NCT00591162 · Status: TERMINATED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 254

Last updated 2014-06-06

No results posted yet for this study

Summary

Bone metabolism is adversely affected by severe burns in children for a period of time.

Conditions

  • Burn

Interventions

DRUG

Tetracycline

Two courses of IV Tetracycline(10mg./kg./day for two days)separated by a two week interval.

RADIATION

Duel Energy X-Ray Absorptiometry (DEXA)

DEXA before discharge from acute admission and again one year post burn.

PROCEDURE

Bone Biopsy

Bone biopsy to be taken in the operation room at the last skin grafting operation at the site of the iliac crest. A second bone biopsy will be taken one year later post discharge from the acute admission.

Sponsors & Collaborators

  • The University of Texas Medical Branch, Galveston

    lead OTHER

Principal Investigators

  • Klein Gordon, M.D. · U.T.M.B.

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
5 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1992-10-31
Primary Completion
2008-06-30
Completion
2008-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00591162 on ClinicalTrials.gov