SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

Summary

This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular fibrillation.

Conditions

• Ventricular Fibrillation
• Cardiac Arrest

Interventions

DEVICE

Automated external defibrillator (Philips FR2+ AED)

Patients in this arm will be provided with immediate defibrillatory shock coupled with otherwise standard resuscitative efforts.

DEVICE

SmartCPR

Patient in this arm will be treated with standard resuscitation efforts except that the first AED analysis will utilize an waveform-based algorithm to recommend either immediate defibrillation or delayed defibrillation for each patient.

OTHER

Delayed defibrillation

In New York City only, all patients not initially treated by study personnel will receive other regional standard for resuscitation - delayed defibrillation.

Sponsors & Collaborators

• Philips Medical Systems

  collaborator INDUSTRY

• London Ambulance Service

  collaborator OTHER

• New York City Fire Department

  lead OTHER_GOV

Principal Investigators

• John P Freese, MD · New York City Fire Department

• Bradley J Kaufman, MD, MPH · New York City Fire Department

• Rachael Donohoe, PhD · London Ambulance Service

• Dawn Jorgenson, PhD · Philips Medical Systems

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

SINGLE_GROUP

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2006-05-31

Primary Completion

2009-06-30

Completion

2009-06-30

Countries

• United States
• United Kingdom

Study Locations