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Pilot Study to Identify the Influence of Genetic Profile Aberrations on Patients With Recurrent Hernias

NCT00527670 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2016-08-08

No results posted yet for this study

Summary

The aim of this study is to compare collagen composition in the skin and fascia of patients with recurrent or incisional hernias versus normal controls. We will identify potential genes responsible for genetic alterations in collagen deposition by using gene chip analysis of the tissue obtained and comparing the hernia group versus controls. The ultimate goal of this study is to identify target genes which may help us eventually predict which patients are at risk for developing post-operative hernias.

Conditions

  • Pathological Processes

Interventions

PROCEDURE

Normal Controls

The control group will have small slivers of tissue removed from the skin and abdomen during surgery to compare genomic information.

PROCEDURE

Recurrent Hernia

This group will have small slivers of tissue removed from the skin and abdomen during hernia repair surgery to find genetic proof of hernias being inherited.

Sponsors & Collaborators

  • University of Missouri-Columbia

    lead OTHER

Principal Investigators

  • Bruce Ramshaw, MD · University of Missouri-Columbia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-08-31
Primary Completion
2010-11-30
Completion
2010-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00527670 on ClinicalTrials.gov