A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain
NCT00513656 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 230
Last updated 2018-10-23
Summary
The purpose of this study is to test the oxycodone/naloxone combination compared to oxycodone alone in patient's specific type of "chronic cancer pain".
Conditions
Interventions
- DRUG
-
Oxycodone
- DRUG
-
Oxycodone/Naloxone
Sponsors & Collaborators
-
Mundipharma Research GmbH & Co KG
lead INDUSTRY
Principal Investigators
-
Sam Ahmedzai · University of Sheffield
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-09-30
- Primary Completion
- 2010-03-31
- Completion
- 2010-06-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain
NCT01167127 ·Status: COMPLETED ·Phase: PHASE3
-
Study Evaluating Safety and Tolerability of Oxycodone in Patients With Moderate to Severe Cancer Pain
NCT03176121 ·Status: COMPLETED ·Phase: PHASE4
-
To Demonstrate Equivalence in Analgesic Efficacy & Bowel Function Between OXN PR Higher Dose & Lower Dose Tablet Strengths in Subjects With Non-cancer or Cancer Pain
NCT02321397 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain
NCT06897917 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain
NCT05265052 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Clinical Study of KW-2246 in Patients With Cancer Pain
NCT00355628 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy
NCT01438567 ·Status: COMPLETED ·Phase: PHASE3
-
Opioid Rotation Versus Combination for Chronic Uncontrolled Cancer Pain
NCT00478101 ·Status: COMPLETED ·Phase: PHASE2
-
Oxycodone or Standard Pain Therapy in Treating Patients With Cancer Pain
NCT00378937 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacokinetic (PK) Study of OxyNorm Injections in Chinese Patient
NCT01482936 ·Status: COMPLETED ·Phase: PHASE1
-
Opioid Misuse in Patients with Cancer
NCT06489769 ·Status: RECRUITING
-
A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients
NCT01313780 ·Status: COMPLETED ·Phase: PHASE4
-
Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain
NCT00634010 ·Status: TERMINATED ·Phase: PHASE3
-
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
NCT00916890 ·Status: SUSPENDED ·Phase: PHASE4
-
Opiophobia in Adults With Advanced Cancer
NCT07093567 ·Status: ACTIVE_NOT_RECRUITING
-
An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.
NCT02660229 ·Status: COMPLETED ·Phase: PHASE4
-
European Study of Opioid Induced Constipation
NCT05149833 ·Status: COMPLETED
-
OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients
NCT02880475 ·Status: COMPLETED ·Phase: PHASE1
-
Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy
NCT00904280 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety and Effectiveness of Fentanyl-TTS Compared to Weak Opioids in Patients With Moderate to Severe Chronic Cancer Pain Previously Treated With NSAIDS (Non-steroidal Anti-inflammatory Drugs).
NCT00576017 ·Status: COMPLETED ·Phase: PHASE4
-
Naldemedine in Clinical Practice in Cancer Patients With Opioid Induced CONstipation: Clinical Outcomes and Patient Experience
NCT07231796 ·Status: RECRUITING
-
Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain
NCT03564548 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids
NCT00589823 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain
NCT03176199 ·Status: COMPLETED ·Phase: PHASE4
-
Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer Pain
NCT01428583 ·Status: COMPLETED ·Phase: PHASE3