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Folic Acid in Preventing Colorectal Polyps in Patients With Previous Colorectal Polyps

NCT00512850 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 672

Last updated 2017-03-03

No results posted yet for this study

Summary

RATIONALE: Chemoprevention is the use of certain substances to keep cancer from forming. The use of folic acid may prevent colorectal cancer.

PURPOSE: This randomized clinical trial is studying how well folic acid works compared with a placebo in preventing colorectal polyps in patients who have had previous colorectal polyps.

Conditions

  • Adenoma of Large Intestine

Interventions

DIETARY_SUPPLEMENT

Folic acid

Intervention group 1g folic acid per day

OTHER

Placebo

One placebo pill per day

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Dana-Farber/Brigham and Women's Cancer Center

    collaborator OTHER

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Edward L. Giovannucci, MD, ScD · Dana-Farber/Brigham and Women's Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1996-05-31
Primary Completion
2004-03-31
Completion
2017-02-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00512850 on ClinicalTrials.gov