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In Vivo Confocal Scanning Laser Microscopy of Benign Nevi

NCT00487864 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2007-06-19

No results posted yet for this study

Summary

In vivo confocal laser scanning microscopy (CLSM) offers the possibility to non-invasively investigate skin lesions at nearly histologic resolution. A recent study showed a high sensitivity (97.6%) and specificity (88.15%) for the discrimination of clinical clear cut melanocytic lesions. CSLM provides horizontal images and can be seen as missing link between dermoscopy and histopathology. For a more accurate diagnosis of dermoscopically difficult to diagnose melanocytic skin lesions in the grey zone between nevus and melanoma, the knowledge of CLSM features of benign nevi seems to be essential. We investigated 30 flat benign nevi with different dermoscopic patterns (10 reticular, 10 globular, 10 homogeneous) nevi. CLSM images were assessed in terms of cytomorphologic and architectural criteria. Different dermoscopic patterns of benign nevi are reflected in different architectural features in CLSM.

Conditions

  • Nevus

Sponsors & Collaborators

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Rainer Hofmann-Wellenhof, Prof. · Department of Dermatology, Medical University Graz, Austria

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-09-30
Completion
2007-05-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00487864 on ClinicalTrials.gov