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The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients

NCT00480870 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2007-12-04

No results posted yet for this study

Summary

The purpose of this study is to determine the effects of the anticholinesterase drug donepezil on sleep in Alzheimer disease patients. Sleep structure and respiratory parameters will be analyzed by polysomnography.

Conditions

  • Alzheimer Disease
  • Sleep Apnea, Obstructive

Interventions

DRUG

donepezil

donepezil 5 mg 1 p / day for 1 month and 2p / day for 5 months on.

DRUG

Placebo

Placebo 1p / day for 1 month and 2 / day for 5 months on

Sponsors & Collaborators

  • Fundação de Amparo à Pesquisa do Estado de São Paulo

    collaborator OTHER_GOV

  • Associacao Fundo de Incentivo a Psicofarmcologia

    lead OTHER

Principal Investigators

  • Walter AS Moraes, MD PhD · Associação Fundo de Incentivo a Psicofarmacologia - AFIP

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-04-30
Completion
2005-01-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00480870 on ClinicalTrials.gov