Effect of Low Molecular Weight Heparin: Tinzaparin in Lung Tumours (TILT)
NCT00475098 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 553
Last updated 2016-09-02
Summary
Experiments suggest that low molecular weight heparin (LMWH) inhibits tumor growth and metastasis. Studies in humans suggest that LMWH is associated with a higher survival in patients with cancer related thrombosis. Two recent studies suggest that LMWH may increase the survival of patients with cancer who do not have an associated thrombosis. The purpose of the study is to assess the effect of LMWH on the overall survival of patients with localized non-small cell lung cancer after complete surgical resection.
Conditions
- Lung Cancer
- Non Small Cell Lung Cancer
Interventions
- DRUG
-
Tinzaparin sodium 100 UI/Kg/OD for 12 weeks
treatment in lung tumours
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Guy Meyer, MD · Assistance Publique - Hôpitaux de Paris
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-06-30
- Primary Completion
- 2016-08-31
- Completion
- 2016-08-31
Countries
- France
Study Locations
More Related Trials
-
Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy
NCT03080883 ·Status: COMPLETED ·Phase: PHASE3
-
Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec
NCT02014441 ·Status: COMPLETED ·Phase: PHASE2
-
Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma
NCT01861301 ·Status: TERMINATED ·Phase: PHASE2
-
Rivaroxaban in the Treatment of Venous Thromboembolism (VTE) in Cancer Patients
NCT02583191 ·Status: TERMINATED ·Phase: PHASE3
-
Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
NCT02601209 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors
NCT01155258 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)
NCT05668949 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy
NCT01580618 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line
NCT04281524 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Study of Telintra for Treatment of Chemotherapy Induced Neutropenia in Patients With Non-Small Cell Lung Cancer
NCT00701870 ·Status: TERMINATED ·Phase: PHASE2
-
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
NCT03886311 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer
NCT04586270 ·Status: TERMINATED ·Phase: PHASE1
-
Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell Carcinoma
NCT00108121 ·Status: COMPLETED ·Phase: PHASE2
-
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT04550494 ·Status: RECRUITING ·Phase: PHASE2
-
Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery
NCT01497444 ·Status: COMPLETED ·Phase: PHASE1
-
Cabozantinib in Combination With Pembrolizumab for the Treatment of Patients With Locally Advanced, Metastatic, or Unresectable Adrenal Cortical Cancer
NCT06006013 ·Status: RECRUITING ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function
NCT00118170 ·Status: COMPLETED ·Phase: PHASE1
-
AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma
NCT00659360 ·Status: COMPLETED ·Phase: PHASE2
-
PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities
NCT01325688 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma
NCT01005472 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of TKI258 in Advanced/Metastatic Melanoma Subjects
NCT00303251 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma
NCT04535271 ·Status: RECRUITING ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma
NCT00245102 ·Status: COMPLETED ·Phase: PHASE2
-
ABT-510 in Treating Patients With Metastatic Melanoma
NCT00602199 ·Status: COMPLETED ·Phase: PHASE2
-
Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery
NCT01553539 ·Status: COMPLETED ·Phase: PHASE2