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Diindolylmethane in Treating Patients With Abnormal Cervical Cells

NCT00462813 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 3000

Last updated 2013-08-07

No results posted yet for this study

Summary

RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of diindolylmethane, a substance found in cruciferous vegetables, may keep cervical intraepithelial neoplasia or cervical cancer from forming.

PURPOSE: This randomized phase III trial is studying diindolylmethane to see how well it works compared to a placebo in treating patients with abnormal cervical cells.

Conditions

Interventions

DRUG

oral microencapsulated diindolylmethane

GENETIC

polymerase chain reaction

OTHER

cervical Papanicolaou test

OTHER

cytology specimen collection procedure

PROCEDURE

colposcopic biopsy

Sponsors & Collaborators

  • Barts and the London School of Medicine and Dentistry

    lead OTHER

Principal Investigators

  • Peter Sasieni, MD · Barts and the London School of Medicine and Dentistry

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-10-31
Primary Completion
2008-06-30
Completion
2010-01-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00462813 on ClinicalTrials.gov