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Myogenic and Osteogenic Responses to eXercise and Ibuprofen

NCT00462722 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 159

Last updated 2015-11-02

Study results available
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Summary

The purpose of this study is to determine if the use of ibuprofen blocks the benefits of exercise to build bone and muscle mass.

Conditions

  • Aging
  • Physical Fitness

Interventions

DRUG

Ibuprofen

400 mg with each exercise session (up to 5 days per week) for 9 months

DRUG

Placebo

with each exercise session (up to 5 days per week) for 9 months

BEHAVIORAL

musculoskeletal-loading exercise

Exercise training program designed to increase bone and muscle mass, including weight lifting and weight-bearing exercises such as jumping in place and treadmill walking up to 5 days per week for 9 months

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Wendy Kohrt, PhD · University of Colorado, Denver

Study Design

Allocation
RANDOMIZED
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2011-12-31
Completion
2011-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00462722 on ClinicalTrials.gov