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HPV Testing for Cervical Cancer Screening Study

NCT00461760 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25223

Last updated 2019-06-19

No results posted yet for this study

Summary

This is a randomised controlled trial of HPV testing with cytology triage for HPV positive women compared to liquid-based cervical cytology (LBC). Although LBC is not widely used for cervical cancer screening in Canada at present, the Pan-Canadian Cervical Cancer Forum has recommended its use and as it is likely to be the standard of care by the time these data are published, the trial has been designed to account for this. Further, LBC will improve the cost-effectiveness of HPV testing because the LBC medium is suitable for both HPV testing as well as cytology and thereby allows the triage testing to be undertaken from the same sample without having to recall the women.

Conditions

  • Cervical Cancer Screening

Interventions

PROCEDURE

Cervical cancer screening undertaken by HPV testing as a single primary screening test with cytology triage of women who are HPV positive

See Detailed Description.

PROCEDURE

Cervical cancer screening undertaken by HPV testing as a single primary screening test with cytology triage of women who are HPV positive

See detailed description.

Sponsors & Collaborators

  • Canadian Institutes of Health Research (CIHR)

    collaborator OTHER_GOV

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Andrew Coldman, PhD · University of British Columbia

  • Gina Ogilvie, MD · University of British Columbia

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2017-04-30
Completion
2018-06-30

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00461760 on ClinicalTrials.gov