Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself
NCT00457678 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2017-08-23
Summary
The purpose of this study is to demonstrate that Visudyne-Lucentis-dexamethasone (V-L-D) triple therapy will give similar efficacy and safety results as Lucentis monotherapy.
Conditions
- Age Related Macular Degeneration
Interventions
- DRUG
-
Visudyne
- DRUG
-
Lucentis
- DRUG
Sponsors & Collaborators
-
QLT Inc.
collaborator INDUSTRY -
Vitreous -Retina- Macula Consultants of New York
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2007-12-04
- Completion
- 2007-12-04
More Related Trials
-
Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)
NCT01301443 ·Status: COMPLETED ·Phase: PHASE1
-
Monocentric Retrospective Observational Study on Patients With Macular Degeneration
NCT02089503 ·Status: UNKNOWN
-
A Phase 1, Safety, Tolerability and Pharmacokinetic Profile of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) in Subjects With Neovascular Age-Related Macular Degeneration
NCT00569140 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II/III Study of the Efficacy and Safety of MacuCLEAR MC-1101 in Treating DryAge-Related Macular Degeneration
NCT02127463 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy
NCT02435862 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Combination of Anecortave Acetate and Triamcinolone Acetonide for the Treatment of Exudative Age-Related Macular Degeneration (AMD)
NCT00211419 ·Status: COMPLETED ·Phase: PHASE1
-
Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjects
NCT03211234 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD)
NCT00473928 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I/II Safety Study of DE-120 Injectable Solution for Age-related Macular Degeneration
NCT02022501 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration
NCT00766337 ·Status: TERMINATED ·Phase: PHASE2
-
A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degeneration
NCT02873351 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Tolerability Study for Age-Related Macular Degeneration
NCT01485588 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II/III Study of Anti-VEGF in Neovascular AMD
NCT00021736 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO)
NCT01027650 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular Degeneration
NCT03869684 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)
NCT00658619 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Squalamine Lactate Ophthalmic Solution, 0.2% in Subjects With Neovascular Age-Related Macular Degeneration
NCT02511613 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Efficacy of a New Treatment as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment in Patients With Age-Related Macular Degeneration (AMD)
NCT00511706 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Patients With Wet AMD
NCT02543229 ·Status: COMPLETED ·Phase: PHASE1
-
Open-Label Posterior Juxtascleral Injections of Anecortave Acetate 15mg Dose for Long Term Use in Patients With AMD
NCT00065728 ·Status: TERMINATED ·Phase: PHASE3
-
Intravitreal Injections of rhuFab V2 in Combination With Visudyne in Subjects With Age Related Macular Degeneration (AMD)
NCT00056823 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Visudyne® in Occult (VIO)
NCT00121407 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of R:GEN as Intervention in Subjects With Early Stages of AMD for Safety and Exploratory Efficacy Outcomes
NCT04776031 ·Status: COMPLETED ·Phase: NA
-
20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD)
NCT01175395 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Eyes That Do Not Meet the Eligibility Criteria of Clinical Trials on Age-Related Macular Degeneration: Proportion of the Real-World Patient Population and Reasons for Exclusion
NCT04836143 ·Status: COMPLETED