Early Indicators of Chronic Rejection in Lung Transplant
NCT00449332 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2016-09-20
Summary
The purpose of this research is to discover the different patterns of cytokine production in patients who may develop Bronchiolitis Obliterans Syndrome-0p (BOS-0p) which means ongoing rejection. This is an early indicator of chronic rejection in lung transplant recipients. These cytokines can be detected in the bronchoalveolar (lung) and tissue samples of lung transplant recipients.
Conditions
- Chronic Rejection in Lung Transplant
- Cytokine Production in Bos Post Lung Transplant
Sponsors & Collaborators
-
University of Chicago
lead OTHER
Principal Investigators
-
Sangeeta M Bhorade, MD · University of Chicago
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-03-31
- Primary Completion
- 2013-12-31
- Completion
- 2013-12-31
Countries
- United States
Study Locations
More Related Trials
-
Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis
NCT06164093 ·Status: COMPLETED ·Phase: NA
-
Analyzing Lung Tissue in People With and Without Chronic Obstructive Pulmonary Disease Who Are Undergoing Lung Transplantation
NCT00756522 ·Status: COMPLETED
-
Microparticles and Bronchiolitis Obliterans Syndrome
NCT02458274 ·Status: COMPLETED
-
Prospective Evaluations of Infectious Complication in Lung Transplant Recipients
NCT00177918 ·Status: COMPLETED
-
A Retrospective Chart Review Study of Patients With Chronic Lung Allograft Dysfunction-Bronchiolitis Obliterans Syndrome (CLAD-BOS) Post Lung Transplantation
NCT06503770 ·Status: COMPLETED
-
LCI and Bronchial Inflammation in Patients With BO
NCT02495597 ·Status: COMPLETED
-
Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children
NCT06352944 ·Status: NOT_YET_RECRUITING
-
Clinical Outcomes and Molecular Phenotypes in Smokers With Parenchymal Lung Disease
NCT02055222 ·Status: COMPLETED
-
Changes in Leukotrienes During Cardiac Surgery in Patients With Chronic Obstructive Pulmonary Disease
NCT00734266 ·Status: COMPLETED
-
Exhaled Breath Condensate Assessment in Stable Non-Cystic Fibrotic Bronchiectasis
NCT03643263 ·Status: COMPLETED
-
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals
NCT00001462 ·Status: COMPLETED
-
Pulmonary Care and Research Collaborative Patient Registry
NCT05445817 ·Status: UNKNOWN
-
A Study of the Natural Progression of Interstitial Lung Disease (ILD)
NCT00470327 ·Status: RECRUITING
-
Current Status of Diagnosis, Treatment and Quality of Life for Patients with Idiopathic Pulmonary Fibrosis
NCT06629623 ·Status: ENROLLING_BY_INVITATION
-
Mechanisms and Targeted Therapy of Airway Basal Cell Dysfunction in Bronchiolitis Obliterans Syndrome
NCT07018804 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Evaluating Clonogenic Epithelial Cell Populations in Patients With Bronchiolitis Obliterans Syndrome
NCT04604522 ·Status: RECRUITING
-
Effects of Hypoxia and Inflammation on Citrulline Synthesis by Ornithine Transcarbamylase in Human Enterocytes
NCT02820064 ·Status: UNKNOWN ·Phase: NA
-
Mapping Chemical and Microbiological Heterogeneity Throughout Explanted Cystic Fibrosis Lung Specimens
NCT02128711 ·Status: COMPLETED
-
Definition of the Status of the Human Lung Stem Cell Niches ex Vivo in Tissue Biopsies Performed in Patients With Emphysema and Interstitial Fibrosis
NCT02705144 ·Status: UNKNOWN
-
Development of a Noninvasive Method of Evaluation of Pulmonary Inflammation in the Condensates of Exhaled Air
NCT00356629 ·Status: TERMINATED
-
The Role of Airway Microbiota on Clinical Phenotypes and Disease Severity in Bronchiectasis
NCT05068518 ·Status: UNKNOWN
-
Development of Airway Absorption Sampling Methods
NCT04494334 ·Status: WITHDRAWN
-
Exploratory Study on Link Between Dynamic Hyperinflation and Lung Clearance Index in Cystic Fibrosis
NCT03323983 ·Status: COMPLETED
-
Prospective Study for Transplant Optimization Using Functional Imaging (TROFI)
NCT02488304 ·Status: TERMINATED ·Phase: PHASE2
-
SD, IL-13 Production Rate in IPF
NCT00532233 ·Status: COMPLETED ·Phase: PHASE2