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Exploration of the Synovial Fluid Inflammation Mediators Under Diacerhein in Knee Osteoarthritis

NCT00440661 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2010-03-04

No results posted yet for this study

Summary

Some inflammation mediators, notably IL-1, are implied in the joint degeneration phenomena of osteoarthritis. The aim of this study is to confirm in vivo the favourable effect of diacerhein on IL-1 and also to appreciate its effect on other synovial inflammation mediators.

Conditions

Interventions

DRUG

Diacerhein

Sponsors & Collaborators

  • Laboratoires NEGMA

    lead INDUSTRY

Principal Investigators

  • Jean-Pierre RAYNAULD, MD · Institut de Rhumatologie de Montreal

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2008-10-31
Completion
2008-10-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00440661 on ClinicalTrials.gov