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The Effect Of A Controlled Daily Skin Care Regimen On Retinoic Acid Tolerance

NCT00440024 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2020-03-13

No results posted yet for this study

Summary

Sun-damaged skin, caused by chronic exposure to ultraviolet (UV) light, is characterized by features such as wrinkling, uneven skin color, roughness and brown spots. An effective treatment for sun-damage that is commonly prescribed is topical retinoic acid (RA). However, the major drawback of topical RA use has been frequently observed irritation characterized by redness, dry skin and severe itching. In this study, we examine whether a daily skin care regimen comprised of an ultra mild cleanser and an effective moisturizer can help improve tolerance to RA treatment.

Conditions

  • Sun-Damaged Skin
  • Retinoid Intolerance

Interventions

DRUG

Tazorac

Tazarotene 0.1% cream applied to the face once daily before bed

DRUG

Dove Mild Cleanser

Ultra mild cleanser: Dove Non-foaming cleansing lotion

DRUG

Dove Facial Moisturizer

Moisturizing cream - Dove facial moisturizer with SPF 15

Sponsors & Collaborators

Principal Investigators

  • Dana Sachs, MD · University of Michigan

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
40 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-02-28
Primary Completion
2009-11-30
Completion
2009-11-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00440024 on ClinicalTrials.gov