H2 Haplotype and CYP3As Polymorphisms and the Antiplatelet Response to Clopidogrel
NCT00433784 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2012-08-21
Summary
The purpose of this study was to assess whether interpatient variability in the platelet response to clopidogrel is partly due to polymorphisms of the hepatic cytochrome P450 (CYP450)3A and of the clopidogrel-P2Y12 receptor genes.
Conditions
- Coronary Artery Disease
- Elective Percutaneous Coronary Intervention
Interventions
- DRUG
-
Clopidogrel
- PROCEDURE
-
Blood sampling - platelet aggregation
- PROCEDURE
-
Blood sampling - genotyping
Sponsors & Collaborators
-
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
lead OTHER
Principal Investigators
-
Jean G Diodati, MD · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-09-30
- Completion
- 2006-04-30
Countries
- Canada
Study Locations
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