T-Cell Response in Patients Receiving Trastuzumab and/or Chemotherapy for HER2-Positive Solid Tumors
NCT00433407 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2012-10-04
Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors predict how well patients will respond to treatment. It may also help the study of cancer in the future.
PURPOSE: This laboratory study is looking at blood samples from patients receiving trastuzumab and/or chemotherapy for HER2-positive solid tumors to assess T-cell response.
Conditions
- Breast Cancer
- Lung Cancer
- Ovarian Cancer
- Prostate Cancer
- Sarcoma
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- BIOLOGICAL
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Mark D. Pegram, MD · Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-08-31
- Primary Completion
- 2006-02-28
Countries
- United States
Study Locations
More Related Trials
-
Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
NCT01275677 ·Status: COMPLETED ·Phase: PHASE3
-
Studying Blood and DNA Samples From Patients With Breast Cancer Treated With Chemotherapy With or Without Trastuzumab
NCT01562288 ·Status: COMPLETED
-
Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy
NCT00001440 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized Trial With Trastuzumab Versus Observation in Breast Cancer Patients
NCT00429247 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab and External Beam Radiation Therapy in Treating Women With Stage III or Stage IV Breast Cancer
NCT00943410 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Herceptin (Trastuzumab) in Combination With a Taxane in Participants With HER2-Positive Breast Cancer Who Relapsed After (Neo)Adjuvant Herceptin Treatment
NCT01301729 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine Versus the Combination of Trastuzumab Plus Docetaxel in Patients With HER2-positive Breast Cancer
NCT02144012 ·Status: TERMINATED ·Phase: PHASE3
-
Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab
NCT00194714 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors
NCT06027983 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
A Safety and Tolerability Study of Assisted and Self-Administered Subcutaneous (SC) Herceptin (Trastuzumab) as Adjuvant Therapy in Early Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
NCT01566721 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel With or Without Trastuzumab in Treating Patients With or Without HER-2/Neu Breast Cancer That is Inoperable, Recurrent, or Metastatic
NCT00003440 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer
NCT00950300 ·Status: COMPLETED ·Phase: PHASE3
-
Trastuzumab Rezetecan Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC
NCT07047755 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Advanced and/or Metastatic Breast Cancer
NCT02748213 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage IV Breast Cancer
NCT00791037 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of the Safety of Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Early and Locally Advanced Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
NCT01940497 ·Status: COMPLETED ·Phase: PHASE3
-
Trastuzumab and Interleukin-2 in Treating Patients With Metastatic Breast Cancer
NCT00006228 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab Emtansine(T-DM1) After Trastuzumab Deruxtecan(T-DXd) in HER2-Positive Breast Cancer in Korea
NCT06928818 ·Status: RECRUITING
-
Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast Cancer
NCT00667251 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
NCT04494425 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Trastuzumab Plus Docetaxel in Treating Women With Recurrent or Metastatic Breast Cancer
NCT00006104 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab Plus Paclitaxel in Treating Women With Metastatic Breast Cancer That Overexpresses HER2
NCT00005635 ·Status: COMPLETED ·Phase: PHASE2
-
Herceptin (Trastuzumab) in Treating Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Primary Breast Cancer
NCT00045032 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 2 Study of Standard Chemotherapy With Trastuzumab, Plus or Minus Pertuzumab, for Pre-treated Metastatic Breast Cancer
NCT02229149 ·Status: TERMINATED ·Phase: PHASE2
-
A Dose-Finding Study of Subcutaneous Herceptin (Trastuzumab) in Healthy Male Volunteers and Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Females
NCT00800436 ·Status: COMPLETED ·Phase: PHASE1