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Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus

NCT00431756 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2025-12-16

No results posted yet for this study

Summary

The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can warn of a progression to esophageal cancer.

Conditions

  • Barrett Esophagus
  • Esophageal Neoplasm
  • Gastroesophageal Reflux

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • National Cancer Institute (NCI)

    collaborator NIH

  • Johns Hopkins University

    lead OTHER

Principal Investigators

  • Marcia Canto, M.D. · Johns Hopkins University

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-05-01
Primary Completion
2023-05-01
Completion
2026-06-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00431756 on ClinicalTrials.gov