Epothilone ZK-219477 in Treating Patients With Recurrent Glioblastoma
NCT00424060 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 38
Last updated 2012-09-24
Summary
RATIONALE: Drugs used in chemotherapy, such as epothilone ZK-219477, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
PURPOSE: This phase II trial is studying how well epothilone ZK-219477 works in treating patients with recurrent glioblastoma.
Conditions
Interventions
- DRUG
-
sagopilone
- GENETIC
-
fluorescence in situ hybridization
- GENETIC
-
gene expression analysis
- OTHER
-
immunohistochemistry staining method
- OTHER
-
laboratory biomarker analysis
- OTHER
-
pharmacological study
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Roger Stupp, MD · Centre Hospitalier Universitaire Vaudois
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-12-31
- Primary Completion
- 2007-08-31
Countries
- Switzerland
Study Locations
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