Gefitinib and PEG-Interferon Alfa-2a in Treating Patients With Unresectable or Metastatic Skin Cancer
NCT00423397 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2013-12-19
Summary
RATIONALE: Gefitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PEG-interferon alfa-2a may interfere with the growth of tumor cells and slow the growth of skin cancer. Giving gefitinib together with PEG-interferon alfa-2a may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of PEG-interferon alfa-2a when given together with gefitinib and to see how well they work in treating patients with unresectable or metastatic skin cancer.
Conditions
- Non-melanomatous Skin Cancer
Interventions
- BIOLOGICAL
-
PEG-interferon alfa-2a
- DRUG
-
gefitinib
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of California, San Diego
lead OTHER
Principal Investigators
-
William L. Read, MD · University of California, San Diego
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-09-30
- Primary Completion
- 2008-01-31
Countries
- United States
Study Locations
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