Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
NCT00421369 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2013-03-22
Summary
In this project we aim to further refine indications for the use of the thyroid hormone - T3 for patients suffering from depression. We aim to identify a sub-group of patients who are more likely to respond to T3 and establish the time in the treatment course when T3 should be added. The results of this project could have significant, direct clinical implications.
Conditions
Interventions
- DRUG
-
sertraline
- DRUG
-
triiodothyronine (T3)
- DRUG
-
reboxetine
Sponsors & Collaborators
-
Hadassah Medical Organization
lead OTHER
Principal Investigators
-
Rena Cooper-Kazaz, MD · Hadassah Medical Organization
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-09-30
- Completion
- 2011-08-31
Countries
- Israel
Study Locations
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