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The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography

NCT00420862 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 2400

Last updated 2007-01-11

No results posted yet for this study

Summary

High survival rates have been reported for screen-detected Stage I lung cancer patients, but there are concerns about the potential biases of uncontrolled studies. DANTE is a prospective randomized controlled trial exploring the effects of screening with LDCT on lung-cancer-specific mortality, and on the prevalence and incidence rates of lung cancer, stage distribution and resectability rates in a selected high-risk population. The prevalence of a set of biomarkers in sputum and blood samples is also being determined.

Conditions

Interventions

PROCEDURE

Spiral Computed Tomography

Sponsors & Collaborators

  • Lega Italiana per la Lotta contro i Tumori

    collaborator OTHER

  • Istituto Clinico Humanitas

    lead OTHER

Principal Investigators

  • Gianni Ravasi, MD · Istituto Clinico Humanitas

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
74 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-06-30
Completion
2010-02-28

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00420862 on ClinicalTrials.gov