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Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

NCT00414011 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2013-07-17

Study results available
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Summary

The purpose of this study is a prospective,double-blinded, randomized trial to compare the rate of healing following PRK after the use of two commercially available 4th generation fluoroquinolones, moxifloxacin and gatifloxacin.

Conditions

  • Epithelium, Corneal

Interventions

DRUG

Moxifloxacin

1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery

DRUG

Gatifloxacin

1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery

Sponsors & Collaborators

  • Walter Reed Army Medical Center

    lead FED

Principal Investigators

  • KRAIG S. BOWER, MD · Walter Reed Army Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Primary Completion
2005-02-28
Completion
2005-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00414011 on ClinicalTrials.gov