Tandutinib in Treating Patients Who Have Undergone Surgery for Metastatic Kidney Cancer
NCT00408902 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2017-11-22
Summary
This phase II trial is studying how well tandutinib works in treating patients who have undergone surgery for metastatic kidney cancer. Tandutinib may stop the growth of kidney cancer by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving tandutinib after surgery may kill any tumor cells that remain after surgery.
Conditions
- Clear Cell Renal Cell Carcinoma
- Recurrent Renal Cell Cancer
- Stage IV Renal Cell Cancer
Interventions
- DRUG
-
tandutinib
Given orally, 500 mg bid daily
- OTHER
-
laboratory biomarker analysis
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Jorge Garcia · Case Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-11-30
- Primary Completion
- 2008-10-31
- Completion
- 2008-12-31
Countries
- United States
Study Locations
More Related Trials
-
Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer
NCT04022343 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Lenalidomide in Treating Patients With Advanced or Unresectable Kidney Cancer
NCT00403169 ·Status: COMPLETED ·Phase: PHASE2
-
Sunitinib Before and After Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed By Surgery
NCT00747305 ·Status: TERMINATED ·Phase: PHASE1
-
Sunitinib Before and After Surgery in Treating Patients With Stage IV Kidney Cancer
NCT00717587 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Toxicity Study of Sorafenib in Patients With Kidney Cancer
NCT00854620 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or Bevacizumab
NCT00866320 ·Status: COMPLETED ·Phase: PHASE2
-
Cabozantinib-s-malate or Sunitinib Malate in Treating Patients With Previously Untreated Locally Advanced or Metastatic Kidney Cancer
NCT01835158 ·Status: COMPLETED ·Phase: PHASE2
-
Sunitinib Malate in Treating Patients With Unresectable or Metastatic Kidney Cancer or Other Advanced Solid Tumors
NCT00499135 ·Status: COMPLETED ·Phase: PHASE1
-
Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney Cancer
NCT00849186 ·Status: COMPLETED ·Phase: NA
-
A Study of RAD001 and Sunitinib in Metastatic Renal Cell Carcinoma
NCT00422344 ·Status: COMPLETED ·Phase: PHASE1
-
Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery
NCT01061411 ·Status: COMPLETED ·Phase: PHASE1
-
MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma
NCT02724020 ·Status: COMPLETED ·Phase: PHASE2
-
BAY 56-3722 in Treating Patients With Recurrent, Unresectable, or Metastatic Kidney Cancer
NCT00040989 ·Status: WITHDRAWN ·Phase: PHASE2
-
Sunitinib in Treating Patients With Progressive Metastatic Transitional Cell Cancer of the Urothelium
NCT00397488 ·Status: COMPLETED ·Phase: PHASE2
-
Sunitinib in Treating Patients With Kidney Cancer That Has Spread to the Brain
NCT00814021 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium
NCT00112905 ·Status: TERMINATED ·Phase: PHASE2
-
Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed
NCT02761057 ·Status: COMPLETED ·Phase: PHASE2
-
Sunitinib Malate in Patients With Non-Clear Cell Renal Cell Cancer
NCT00465179 ·Status: COMPLETED ·Phase: PHASE2
-
SU5416 in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Previous Treatment
NCT00009919 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase I Study of Bevacizumab and Sunitinib in Metastatic Renal Cell Carcinoma Patients
NCT00421512 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib in Treating Patients Who Are Undergoing Surgery for Metastatic Kidney Cancer
NCT00126659 ·Status: TERMINATED ·Phase: PHASE2
-
Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery
NCT01164228 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic or Unresectable Kidney Cancer
NCT00496756 ·Status: TERMINATED ·Phase: PHASE2
-
Sunitinib and Irradiated Donor Lymphocytes in Treating Patients With Metastatic Kidney Cancer
NCT00853125 ·Status: TERMINATED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
NCT00727532 ·Status: TERMINATED ·Phase: NA