Prospective Randomized Trial Between WBRT Plus SRS Versus SRS Alone for 1-4 Brain Metastases
NCT00406835 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 180
Last updated 2006-12-04
Summary
The purpose of this study is to determine if WBRT combined with SRS resulted in improvements in survival, brain tumor control, functional preservation rate, and frequency of neurologic death.
Conditions
- Brain Metastasis
Interventions
- PROCEDURE
-
Whole-Brain Radiation Therapy, Stereotactic Radiosurgery
Sponsors & Collaborators
-
Hokkaido University Hospital
lead OTHER
Principal Investigators
-
Hidefumi Aoyama, MD, PhD · Hokkaido University School of Medicine
-
Hiroki Shirato, MD, PhD · Hokkaido University School of Medicine
-
Keiichi Nakagawa, MD, PhD · Tokyo University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-10-31
- Completion
- 2005-04-30
Countries
- Japan
Study Locations
More Related Trials
-
Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
NCT01372774 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases
NCT05438212 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Radiation Therapy With or Without Surgery in Treating Patients Who Have Brain Metastases
NCT00003324 ·Status: COMPLETED ·Phase: NA
-
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
NCT03741673 ·Status: RECRUITING ·Phase: PHASE3
-
Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis
NCT00484978 ·Status: UNKNOWN ·Phase: PHASE2
-
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
NCT00377156 ·Status: COMPLETED ·Phase: PHASE3
-
Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
NCT04365374 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
NCT03750227 ·Status: RECRUITING ·Phase: PHASE3
-
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
NCT04114981 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Phase I Trial of Stereotactic Radiosurgery Following Surgical Resection of Brain Metastases
NCT01395407 ·Status: COMPLETED ·Phase: PHASE1
-
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases
NCT01644591 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Fractionated Stereotactic Radiosurgery to Treat Large Brain Metastases
NCT00928226 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases
NCT01592968 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy
NCT00548756 ·Status: COMPLETED ·Phase: PHASE3
-
Elective Simultaneous Modulated Accelerated Brain Radiation Therapy for NSCLCs With Limited Brain Metastases
NCT03414944 ·Status: UNKNOWN ·Phase: NA
-
Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial
NCT03075072 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
NCT03550391 ·Status: RECRUITING ·Phase: PHASE3
-
The Impact of Neurocognitive Function in Patients With Multiple Brain Metastases Receiving Whole Brain Radiation Therapy
NCT03626818 ·Status: UNKNOWN
-
Stereotactic Radiation Therapy Before Surgery for the Treatment of Resectable Brain Metastases
NCT04069910 ·Status: WITHDRAWN ·Phase: NA
-
Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases
NCT03398694 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases
NCT00950001 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Whole-Brain Radiotherapy (WBRT) Versus WBRT and Integrated Boost Using Helical Tomotherapy for Multiple Brain Metastases
NCT00876759 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer
NCT00096265 ·Status: TERMINATED ·Phase: PHASE3
-
Stereotactic Radiosurgery After Surgery in Treating Patients With Brain Metastases
NCT00814463 ·Status: TERMINATED ·Phase: PHASE2
-
Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
NCT04588246 ·Status: TERMINATED ·Phase: PHASE3