Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors
NCT00394446 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2008-02-13
Summary
Phase 1, Multiple Dose Study of MPC-6827 in Subjects with Refractory Solid Tumors.
Conditions
- Refractory Solid Tumors
Interventions
- DRUG
-
MPC-6827
2-hour intravenous infusion given once weekly for 3 consecutive weeks on a 28 day cycle
Sponsors & Collaborators
-
Myrexis Inc.
lead INDUSTRY
Principal Investigators
-
Margaret Yu, MD · Myrexis Inc.
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-03-31
- Primary Completion
- 2007-04-30
- Completion
- 2008-02-29
Countries
- United States
Study Locations
More Related Trials
-
A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
NCT02298387 ·Status: COMPLETED ·Phase: PHASE1
-
TTP607 in Refractory Solid Malignancies
NCT00939172 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors
NCT01090960 ·Status: COMPLETED ·Phase: PHASE1
-
An Open-label, Single-arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of OriV508 Injection in Treating Relapsed/Refractory Hematological Malignancies
NCT07101705 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study of MGC026 in Participants With Advanced Solid Tumors
NCT06242470 ·Status: RECRUITING ·Phase: PHASE1
-
Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A
NCT03950297 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Vorinostat in Patients With Solid Tumors (MK-0683-029)
NCT00127127 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors
NCT03510104 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MHB042C in Patients With Advanced Solid Tumors
NCT07192107 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase I Study of MK-4827 for Treatment of Solid Tumors (MK-4827-005)
NCT01226901 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Pharmacologic Study of VTX-2337 in Patients With Advanced Cancer
NCT00688415 ·Status: COMPLETED ·Phase: PHASE1
-
Dose-Finding and Safety Study for Oral Single-Agent to Treat Advanced Malignancies
NCT02030067 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
NCT06150664 ·Status: RECRUITING ·Phase: PHASE1
-
BMS-214662 in Treating Patients With Advanced Solid Tumors
NCT00004877 ·Status: COMPLETED ·Phase: PHASE1
-
First in Human Study of M4344 in Participants With Advanced Solid Tumors
NCT02278250 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MK-4827 in Combination With Standard Chemotherapy in Participants With Advanced Solid Tumors (MK-4827-008 AM1)
NCT01110603 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03071757 ·Status: COMPLETED ·Phase: PHASE1
-
Study Evaluating MST-997 in Advanced Malignant Solid Tumors
NCT00088647 ·Status: TERMINATED ·Phase: PHASE1
-
Treatment With MK6592 and an Anti-cancer Drug in Patients With Advanced Solid Tumors (6592-001)
NCT00359671 ·Status: TERMINATED ·Phase: PHASE1
-
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)
NCT05898399 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety Study of MBP-426 (Liposomal Oxaliplatin Suspension for Injection) to Treat Advanced or Metastatic Solid Tumors
NCT00355888 ·Status: COMPLETED ·Phase: PHASE1
-
Study of NMS-1286937 in Adult Patients With Advanced/Metastatic Solid Tumors
NCT01014429 ·Status: COMPLETED ·Phase: PHASE1
-
First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy
NCT02644278 ·Status: COMPLETED ·Phase: PHASE1
-
BMS-188797 in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Treatment
NCT00005611 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Pharmacokinetics of XL647 Administered Orally to Subjects With Solid Tumors
NCT00086528 ·Status: COMPLETED ·Phase: PHASE1