MedTrace Logo

Randomized Trial on Effectiveness of ACTs in Ghana

NCT00374205 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 245

Last updated 2007-11-27

No results posted yet for this study

Summary

The purpose of this study is to compare the effectiveness and safety of two Artemisinin Combination Therapies (ACTs) for the treatment of children with uncomplicated Plasmodium falciparum malaria

Conditions

  • Malaria, Falciparum

Interventions

DRUG

Artesunate plus Amodiaquine

Artesunate 50 mg and Amodiaquine 153 mg co-blister tablets: 3 days once daily weight-adjusted dosing according to manufacturer

DRUG

Artemether-Lumefantrine

Artemether 20 mg/Lumefantrine 120mg fixe-dose-combination tablets: 3 days twice daily weight-adjusted dosing according to manufacturer

Sponsors & Collaborators

  • Presbyterian Health Service (PHS)

    collaborator UNKNOWN

  • Kumasi Centre for Collaborative Research (KCCR)

    collaborator OTHER

  • School of Medical Sciences Kumasi (SMS/KNUST)

    collaborator UNKNOWN

  • Bernhard Nocht Institute for Tropical Medicine

    lead OTHER_GOV

Principal Investigators

  • Daniel Ansong, MD · School of Medical Science (SMS), Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Months
Max Age
59 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-09-30
Completion
2007-10-31

Countries

  • Ghana

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00374205 on ClinicalTrials.gov