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Effect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, Stage II, Stage III Breast Cancer, or Ductal Carcinoma In Situ That Can Be Removed By Surgery

NCT00373191 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2015-10-12

No results posted yet for this study

Summary

RATIONALE: Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.

PURPOSE: This laboratory study is looking at the effects of surgery, radiation therapy, chemotherapy, and hormone therapy on biomarkers in women with stage I, stage II, stage III breast cancer, or ductal carcinoma in situ that can be removed by surgery.

Conditions

Interventions

DRUG

chemotherapy

N/A- not dictated by study

DRUG

endocrine therapy

N/A- not dictated by study

GENETIC

DNA methylation analysis

laboratory analysis

GENETIC

protein analysis

laboratory analysis

OTHER

laboratory biomarker analysis

laboratory analysis

OTHER

questionnaire administration

questionnaire

PROCEDURE

adjuvant therapy

N/A- not dictated by study

PROCEDURE

conventional surgery

N/A- not dictated by study

RADIATION

radiation therapy

N/A- not dictated by study

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    lead OTHER

Principal Investigators

  • Vered Stearns, MD · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-05-31
Primary Completion
2009-02-28
Completion
2013-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00373191 on ClinicalTrials.gov