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Screening for Occult Malignancy in Idiopathic Venous Thromboembolism

NCT00361647 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2008-06-13

No results posted yet for this study

Summary

Prospective controlled randomized study. Aim of this study is to assess the feasibility and sensitivity of CT scanning of the thorax, abdomen and pelvis for the detection of occult cancer in patients with idiopathic venous thromboembolism. Patients presenting with acute idiopathic venous thromboembolism, free from already known cancer and in whom a routine battery screening has excluded the presence of cancer, are randomized to receive either a CT scanning of the thorax, abdomen and pelvis (completed by mammography if not already performed in the past year, and by gastroscopy and/or colonoscopy in patients with positive hemoccult) or a diagnostic programme freely decided by attending physicians. Patients of either group in whom the search for cancer is negative are followed-up for two years to register the development of clinically symptomatic malignant disease. The rate of cancer detection and that of cancer development are compared between the two study groups.

Conditions

  • Venous Thromboembolism

Interventions

PROCEDURE

Diagnostic screening for occult malignancy

Sponsors & Collaborators

  • University of Padova

    lead OTHER

Principal Investigators

  • Paolo Prandoni, MD, PhD · Department of Medical and Surgical Sciences, University of Padua, Italy

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2008-05-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00361647 on ClinicalTrials.gov