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Influence of Angiotensin Converting Enzyme (ACE) Genotype on Lung Diffusion in Heart Failure

NCT00361127 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2016-01-28

No results posted yet for this study

Summary

In patients with chronic heart failure ACE-inhibitor treatment improves lung diffusion and prevents pulmonary edema after fluid overload. In the western country, 3 population types of ACE genotypes exist (DD, ID, II). It is unknown whether the ACE genotype influences the response to fluid overload in ACE-inhibitor treated chronic heart failure patients.

Conditions

  • Heart Failure, Congestive

Interventions

DRUG

isotonic saline infusion

Sponsors & Collaborators

  • Piergiuseppe Agostoni

    lead OTHER

Principal Investigators

  • Piergiuseppe Agostoni, MD.PhD · Centro Cardiologico Monzino

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-08-31
Primary Completion
2013-12-31
Completion
2013-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00361127 on ClinicalTrials.gov