Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy
NCT00361023 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2006-08-07
Summary
Angiotensin type-1 receptor (AT1R) blockers (ARBs) have been recognized recently as regulators of glucose and lipid metabolism in adipocytes and adipose tissue.Moreover telmisartan and irbesartan have been recognized recently as regulators of glucose metabolism. For ARB losartan, the results were controversial. To confirm its effect on glucose metabolism, we designed and performed a prospective, randomized and controlled study in subjects with type 2 diabetes and nephropathy.
Conditions
- Type 2 Diabetes
- Diabetic Nephropathy
Interventions
- DRUG
-
losartan
Sponsors & Collaborators
-
Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
Hui M Jin, MD · Shanghai NO.3 people's Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Completion
- 2006-07-31
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