Omega-3 Fatty Acid Treatment in Multiple Sclerosis

Summary

Based on previous clinical studies indicating beneficial treatment effects of omega-3 fatty acids in multiple sclerosis, and the increasing evidence of anti-inflammatory effects of omega-3 fatty acids, this study aims to evaluate treatment effects of concentrated omega-3 fatty acids (Triomar™) in MS, both as monotherapy and in combination with standard immunomodulatory therapy defined as interferon-beta 1a (Rebif™).

Conditions

• Relapsing-Remitting Multiple Sclerosis

Interventions

DRUG

Triomar™ (omega-3 fatty acids)

Sponsors & Collaborators

• The Multiple Sclerosis National Competence Centre

  collaborator UNKNOWN

• The Norwegian Multiple sclerosis Society

  collaborator UNKNOWN

• Pronova BioPharma

  collaborator INDUSTRY

• Serono Nordic

  collaborator UNKNOWN

• Amersham Health

  collaborator INDUSTRY

• Haukeland University Hospital

  lead OTHER

Principal Investigators

• Kjell-Morten Myhr, MD, PhD · Dep. of Neurology, Haukeland University Hospital

• Antonie G. Beiske, MD · Dep. of Neurology, Akershus University Hospital

• Harald Hovdal, MD · Dep. of Neurology, Trondheim University Hospital

• Rune Midgard, MD, PhD · Dep. of Neurology, Molde Hospital

• Ingrid K. Bjørnå, MD · Dep. of Neurology, Buskerud Hospital

• Olaf A. Henriksen, MD · Dep. of Neurology Nordland Hospital

• Jan Schepel, MD · Dep. of Neurology Haugesund Hospital

• Randi Eikeland, MD · Dep. of Neurology Arendal Hospital

• Terje Kristensen, MD · Dep. of Neurology Fredrikstad Hospital

• Halfdan Kierulf, MD · Dep. of Neurology Rikshospitalet University Hospital

• Frøydis Dalane, MD · Dep. of Neurology, Telemark Hospital

• Alla Bru, MD · Dep. of Neurology, Stavanger University Hospital

• Grethe Kleveland, MD · Dep. of Neurology, Lillehammer Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

55 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2004-12-31

Completion

2008-07-31

Countries

• Norway

Study Locations