Results of Mass Switch From Latanoprost to Travoprost
NCT00347126 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 372
Last updated 2010-05-12
Summary
Prostaglandin analogs are a leading class of glaucoma drugs with a proven safety and efficacy for controlling IOP. They include latanoprost, bimatoprost, travoprost and unoprostone. Recently, the Singapore National Eye Center (SNEC) awarded a tender for prostaglandin analogues to Alcon, the manufacturer of travoprost. Since then, all subsidized patients previously treated with latanoprost were systematically switched to travoprost and this process will continue for the rest of this year. In this study, we propose to prospectively study the efficacy and safety of switching from latanoprost to travoprost in a large series of glaucoma patients at SNEC. A total of 372 consecutive patients being switched from latanoprost to travoprost will be followed up for 12 weeks following the switch. In addition to intraocular pressure, the safety and tolerability (with particular emphasis on hyperemia) of travoprost will be examined.
Conditions
Sponsors & Collaborators
-
Singapore National Eye Centre
lead OTHER_GOV
Principal Investigators
-
Tin Aung, FRCS, PhD · Singapore National Eye Centre
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-04-30
- Completion
- 2008-04-30
Countries
- Singapore
Study Locations
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