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Aortic Stenosis in Elderly : Determinant of Progression

NCT00338676 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 273

Last updated 2017-03-01

No results posted yet for this study

Summary

Aortic stenosis (AS) is AS is caused by calcium deposits in the aortic valve. Calcification is progressive and eventually leads to reduced leaflet motion with obstruction of the left ventricular outflow. The only treatment is surgery. There are evidences that AS is a regulated process with similarities to atherosclerosis but determinants of AS progression are unknown. The study aims at evaluating these determinants and more specifically the role of lipids, inflammation and platelet aggregation.

Conditions

  • Aortic Stenosis
  • Elderly Gravida

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • David Messika-Zeitoun, MD · Assistance Publique des Hopitaux de Paris

Eligibility

Min Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-11-30
Primary Completion
2017-09-30
Completion
2017-09-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00338676 on ClinicalTrials.gov