Phase II Trial of RAD001 in Refractory Colorectal Cancer
NCT00337545 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2007-10-10
Summary
Single center open-label study of an oral agent (RAD001) in subjects with metastatic colorectal cancer refractory to at least 2 standard chemo/biologic regimens.
Conditions
Interventions
- DRUG
-
RAD001
Sponsors & Collaborators
- collaborator INDUSTRY
-
Swedish Medical Center
lead OTHER
Principal Investigators
-
Philip Gold, M.D. · Swedish Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-05-31
- Completion
- 2007-04-30
Countries
- United States
Study Locations
More Related Trials
-
S9923 R115777 in Treating Patients With Advanced Colorectal Cancer
NCT00005833 ·Status: COMPLETED ·Phase: PHASE2
-
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorectal Cancer
NCT00023933 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Trial of LBH589 in Refractory Colorectal Cancer
NCT00690677 ·Status: COMPLETED ·Phase: PHASE2
-
Nitrocamptothecin in Treating Patients With Advanced or Recurrent Colorectal Cancer
NCT00005877 ·Status: UNKNOWN ·Phase: PHASE2
-
Tocladesine in Treating Patients With Recurrent or Progressive Metastatic Colorectal Cancer
NCT00021268 ·Status: UNKNOWN ·Phase: PHASE1
-
Ro 31-7453 in Treating Patients With Recurrent or Refractory Metastatic Colorectal Cancer
NCT00016250 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
NCT00522665 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dabrafenib + Trametinib + PDR001 In Colorectal Cancer
NCT03668431 ·Status: UNKNOWN ·Phase: PHASE2
-
NB1011 in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00031616 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer
NCT00796718 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Capecitabine (Xeloda) in Patients With Metastatic Colorectal Cancer
NCT02567331 ·Status: COMPLETED ·Phase: PHASE4
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal Carcinoma
NCT00215956 ·Status: COMPLETED ·Phase: PHASE1
-
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00032110 ·Status: COMPLETED ·Phase: PHASE2
-
Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery
NCT00433576 ·Status: COMPLETED ·Phase: PHASE1
-
The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urothelium
NCT01801137 ·Status: COMPLETED ·Phase: PHASE2
-
For Prevention of Diarrhea in Patients Diagnosed With Metastatic Colorectal Cancer Treated With Chemotherapy
NCT00037180 ·Status: TERMINATED ·Phase: PHASE2
-
Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
NCT00022698 ·Status: COMPLETED ·Phase: PHASE2
-
Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer
NCT03542877 ·Status: COMPLETED ·Phase: PHASE2
-
Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer
NCT03647839 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy Plus Radiation Therapy in Treating Patients With Unresectable, Residual, or Recurrent Colorectal Cancer
NCT00003704 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy and Avastin Followed by Maintenance Treatment With Avastin +/- Tarceva
NCT00598156 ·Status: COMPLETED ·Phase: PHASE3
-
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
NCT03377361 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer
NCT02096354 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors
NCT03475953 ·Status: RECRUITING ·Phase: PHASE1/PHASE2