Efficacy and Safety of Deep Brain Stimulation (DBS) of the Pallidal (GPi) in Patients With Tardive Dystonia

Summary

The purpose of this randomized, double blind, multi-center study is to assess the efficacy and safety of bilateral pallidal deep brain stimulation in patients with tardive dystonia.

Conditions

• Dystonia
• Movement Disorder

Interventions

PROCEDURE

deep brain stimulation

high frequency stimulation

Sponsors & Collaborators

• Humboldt-Universität zu Berlin

  collaborator OTHER

• Ruhr University of Bochum

  collaborator OTHER

• Medical University of Cologne

  collaborator OTHER

• Heinrich-Heine University, Duesseldorf

  collaborator OTHER

• University Hospital Freiburg

  collaborator OTHER

• Medical University of Hannover

  collaborator OTHER

• Medical University Innsbruck

  collaborator OTHER

• University of Kiel

  collaborator OTHER

• Philipps University Marburg

  collaborator OTHER

• Ludwig-Maximilians - University of Munich

  collaborator OTHER

• University of Rostock

  collaborator OTHER

• University of Regensburg

  collaborator OTHER

• University Hospital Tuebingen

  collaborator OTHER

• Medical University of Vienna

  collaborator OTHER

• Medtronic

  collaborator INDUSTRY

• Charite University, Berlin, Germany

  lead OTHER

Principal Investigators

• Andreas R Kupsch, MD · Dpt. of Neurology, Augustenburger Platz 1, 13353 Berlin, Charite, Campus Virchow, Germany

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2006-05-31

Completion

2010-12-31

Countries

• Germany

Study Locations