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Relationship of Genes and Life Events to Blood Pressure

NCT00327431 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2008-05-22

No results posted yet for this study

Summary

Research suggests that blood pressure is influenced by both genetic and environmental factors. The goal of this study is to find genes that play a role in blood pressure and understand how they interact with life events (such as job stress) to influence blood pressure. We hypothesize that the gene for endothelin-1 is associated with increased blood pressure. Further, we predict that this genetic relationship is moderated by psychosocial stress factors, specifically job strain and marital cohesion.

Conditions

Interventions

GENETIC

Cheek swab samples for DNA

Sponsors & Collaborators

  • Sunnybrook Health Sciences Centre

    lead OTHER

Principal Investigators

  • Brian Baker, MB, ChB · University of Toronto

  • Sheldon Tobe, MD · Sunnybrook Health Sciences Centre

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-11-30
Completion
2007-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00327431 on ClinicalTrials.gov