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Molecular Quantification of Insulin mRNA

NCT00324207 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2010-03-05

No results posted yet for this study

Summary

The objectives of this study are to:

1. quantitate the level of insulin mRNA in the while cell fraction of whole blood in selected groups of subjects,
2. determine the gene expression of markers of white cell activation in the white cell fraction of whole blood in selected subjects,
3. determine the identity of the white cell responsible for expression of insulin mRNA and
4. determine protein expression of mRNA of insulin/proinsulin and selected genes of white cell activation.

Conditions

  • Type 1 Diabetes Mellitus

Sponsors & Collaborators

  • Children's Mercy Hospital Kansas City

    lead OTHER

Principal Investigators

  • Wayne Moore, MD, PhD · Children's Mercy Hospital Kansas City

Eligibility

Min Age
1 Year
Max Age
17 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-02-28
Primary Completion
2009-01-31
Completion
2009-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00324207 on ClinicalTrials.gov