Bevacizumab (Avastin) Induced Hypertension and Correlation With Tumor Response, a Chart Review
NCT00322725 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 25
Last updated 2024-01-11
Summary
1.11 Retrospectively evaluate for a correlation between tumor response and changes in systolic/diastolic/mean arterial blood pressures in patients treated with bevacizumab, with or without chemotherapy, with a wide variety of metastatic malignancies.
1.12 Retrospectively evaluate for differences in tumor response between patients with and without pre-existing hypertension treated with bevacizumab plus or minus chemotherapy with a wide variety of metastatic malignancies.
1.21 Determine if there were differences in bevacizumab induced hypertension rates between different tumor types.
1.22 Evaluate for differences in bevacizumab induced hypertension rates between males and females.
1.23 Examine if there were associations between a particular chemotherapeutic agent(s), that may have had an increased propensity of inducing hypertension when combined with bevacizumab.
Conditions
Sponsors & Collaborators
-
University of New Mexico
lead OTHER
Principal Investigators
-
Fa-Chyi Lee, MD · University of New Mexico
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-02-28
- Primary Completion
- 2009-04-30
- Completion
- 2009-04-30
Countries
- United States
Study Locations
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