Effect Of GW501516X On How The Heart Obtains And Uses Energy
NCT00318617 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2012-03-19
Summary
The purpose of this study is to determine the effect of a 4-week treatment period with GW501516X on how the heart obtains and uses energy. The energy of the heart will be measured by Magnetic Resonance Imaging (MRI). This study will also measure a number of other potential markers of drug activity, including levels of certain lipids (fats) and proteins in your blood. The data from this study may help researchers better understand the actions of this drug in the body and if this drug may be useful to treat patients with heart disease.
Conditions
- Dyslipidaemias
- Heart Failure
Interventions
- DRUG
-
GW510516X
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-12-31
Countries
- United States
Study Locations
More Related Trials
-
A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
NCT05659264 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
NCT07218627 ·Status: RECRUITING ·Phase: PHASE1
-
Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
NCT06017609 ·Status: COMPLETED ·Phase: PHASE2
-
A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
NCT02119260 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Oral PG-116800 Following a Heart Attack
NCT00067236 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.
NCT00353522 ·Status: COMPLETED ·Phase: PHASE2
-
A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants
NCT05044325 ·Status: TERMINATED ·Phase: PHASE1
-
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
NCT07001800 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Cardiovascular Genistein Therapy for Heart Failure Inflammation
NCT06501768 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of APL180
NCT00907998 ·Status: COMPLETED ·Phase: PHASE1
-
An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia
NCT05117346 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD)
NCT00568594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure
NCT03387215 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
NCT00050076 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
NCT01877915 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
NCT01131637 ·Status: TERMINATED ·Phase: PHASE3
-
SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
NCT05852704 ·Status: RECRUITING ·Phase: PHASE3
-
Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency
NCT00745316 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease.
NCT04515290 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess the Safety of BAY1067197 in Stable Heart Failure Patients on Standard Therapy Including ß-blocker
NCT01945606 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of Adenovirus Hepatocyte Growth Factor to Treat Ischemic Heart Disease
NCT01925352 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
NCT06122779 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure
NCT06299826 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective Observation of Cardiac Safety With Proteasome Inhibition
NCT02178579 ·Status: COMPLETED
-
Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF)
NCT06215586 ·Status: COMPLETED ·Phase: PHASE2