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Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years

NCT00307671 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 108

Last updated 2011-09-12

No results posted yet for this study

Summary

The aim of this trial is to lower the morbidity rate in elderly patients affected with systemic necrotizing vasculitides, by reducing mortality and improving global outcome.

Conditions

  • Vasculitis
  • Wegener's Granulomatosis
  • Microscopic Polyangiitis
  • Churg-Strauss Syndrome
  • Polyarteritis Nodosa

Interventions

DRUG

prednisone, methylprednisolone,cyclophosphamides

treatment conventional

DRUG

Cyclophosphamide, Azathioprine,prednisone,methylprednisolone

reduction dose

DRUG

Mycophenolate mofetil,methotrexate

in the treatment conventional and in the reduction dose

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Loïc Guillevin, MD,PhD · Assistance Publique - Hôpitaux de Paris

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-07-31
Primary Completion
2011-07-31
Completion
2011-07-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00307671 on ClinicalTrials.gov